Controversial Science Evaluation: Examples from Molecular Parasitology

Seminar, 3 ECTS, Wednesdays 17:00-18:30; room E02.054 Michael Boshart, Markus Meissner, Nicolai Siegel

Many orginal publications represent the authors interpretation of data that are not always unequivocal and challenged by other researcher´s data.
The aim of this seminar series is to improve critical assessment of primary literature and an appreciation how controversial studies and subsequent discussion are crucial to advance knowledge.
We will use protozoan parasites causing human and veterinary diseases as models focusing on our own research fields. Where possible the students will be asked to discuss two contradicting publications on the same research question.

Prerequisites confident reading and understanding of primary reasearch papers,
willingness to actively participate in critical discussion
Exam regulations presentation quality, active participation and quality of arguments in controversial discussion
Target group all Master programs of Faculty of Biology
interested advanced medical and vet med students
Registration via LSF
presence at first seminar date 23.10.19 is mandatory
Date Topic Lecturer
23.10.19 Introduction to the seminar all
30.10.19 Base J: role in antigenic variation Siegel
06.11.19 Is PKA a universal cAMP-dependent kinase? Boshart
13.11.19 Malaria Vaccines Meissner
20.11.19 Odorant Receptors Siegel
27.11.19 HGF transmigration of malaria sporozoites Meissner
04.12.19 Trypanosome lytic factor Boshart
11.12.19 Protein export: PIP yes or no Meissner
18.12.19 var introns Siegel
08.01.19 Toxo motility: essential or redundant? Meissner
15.01.19 siRNA in Apicomplexa Siegel
22.01.19 Motility and virulence Boshart
29.01.19 Citric acid cycle in malaria Boshart

Literature will be uploaded here after the introduction seminar